Authors: Ibrahim El-Bayoumy.
Aim: To study the relationships between Type 2 diabetes mellitus (DM2) and the risk of hepatocellular carcinoma (HCC).
Methods: We studied the association between DM2 and HCC in a large case-control study that enrolled 255 Egyptian patients with HCC (71.4% males, mean age 62± 10.2 years) matched for age and sex and free from hepatocellular carcinoma 305 patients constituted the control group.
Results: Prevalence of DM2 was significantly higher in HCC patients (29.1.2% vs 10.2.7%; OR = 3.35 95% CI: 1.31-3.29.). The highest prevalence of diabetes was found in patients with hepatitis C was 30% followed by hepatitis B infection 20%.
Conclusion: DM2 in our patients is associated with a 3-fold increase risk of HCC so that we encourage prompt screening for HCC in diabetic patients with cirrhosis.
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