Pushplata Sankhwar, Jaiswar SP, Apurva Goel, Kiran Tiwari.
PCOS affects approximately 4-12% women of reproductive age. For such a common syndrome, there is surprisingly a lack of well-defined diagnostic criteria, making it confusing to doctors. Furthermore, the symptoms of PCOS range from physical to psychological and can also lead to infertility. It was thus, pertinent to deliberate upon more ways of managing PCOS and so the objective of the study was to find out the effect of Standardized Fenugreek seed Extract on reduction in ovarian volume and the number of ovarian cysts.
An open labeled, single armed, single-centric and noncomparative study on 107 female patients suffering from PCOS was conducted using a novel fenugreek seed extract for a period of 12 weeks to determine its efficacy in reduction of ovary volume and number of ovarian cysts.
On completion of the study, significant decrease was noticed in both the ovaries’ volume (p-value 0.0001). More than 65% of the patients showed reduction in cyst size in both left & right ovaries. 15 patients got pregnant by the end of the study and HOMA Index was reduced in 75.67% of the study population. 79.5% of the study population had regular menstrual cycles at the completion of the study and prolactin levels were significantly reduced. Hirsutism score was significantly reduced (p=0.002) at the end of 12 weeks of treatment. No changes were observed on LFT, KFT & Haemogram level.
The fenugreek seeds extract was proven to be safe and effective in treating PCOS in women of reproductive age by reducing the cyst volume in both ovaries as well as cyst sizes.View pdf