Gastroenterology, Hepatology & Digestive Disorders

Abstract

Effect of the Gurgem-7 Traditional Compound on CCL4-Induced Chronic Hepatitis

Hushan, Chimedragchaa Ch, Altantsetseg A, Tsend-Ayush D.

It is necessary to investigate wide range, low side effect, and long-term usage plant origin remedy for hepatobiliary disease. The more perspective medication is polycomponent traditional drug [1]. Study was done on investigation of Gurgem-13 polyprescription [2,3] on experimental chronic hepatitis model by Gi-ppeum Lee, Won-IL Jeong (2005) induced by 10%-1.0 mg/kg – CCl4 three times per week on Wistar bread rats, and following studying of remedy curing results in 1, 2, 3 weeks of experiment. Gurgem-13 traditional prescription was compared with Carsil, and Lilicoaguliant - traditional remedy [4]. The result shown Gurgem-13 is more efficient on lowering AST, ALT enzymes in three months of chronic toxic hepatitis (p=0.15) similar with comparative drugs. More results tell us the Gurgem-13 has an antioxidant effect. Traditional compound Gurgem-13 relieving symptoms of cytolysis, liver function failure, and demonstrated antioxidant, hepatoprotective effect, meantime correcting cholestasis and metabolism of iron in the liver.

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