Authors: Israel Alfonso Trujillo, Yetter Cruz Leon, Mariana Sarao Pineda, Nora Rosales Hernández, Yaquelin Luciana Morales Novo, Jesus Lazaro Diego De la Campa, Angel, Rosa Gutierrez Rojas, Julio Antonio López Silva and Daymi Serpa Almaguer.
Introduction: Platelet rich plasma (PRP) is an autologous serum that contains high concentrations of platelets and growth factors. It is currently a versatile therapy in dermatology; however, few studies objectively evaluate its efficacy.
Objective: To evaluate the efficacy and safety of intradermal microinjection of autologous platelet concentrate (APC) in the treatment of crow's feet rejuvenation.
Method: An observational, analytical and longitudinal study was carried out in 60 patients from the Hospital Clínico Quirúrgico: “Hermanos Ameijeiras”, in the period between March 1, 2017 and March 31, 2020. The treatment was applied monthly. for 1 year. The final evaluation was carried out 3 months after the end of the treatment.
Results: 60 women with an average age of 45 ± 4.3 years were treated. After treatment, there were significant changes in the Glogau Photo Damage Scale (P = 0.0022), in the Photonumeric Scale to assess the severity of crow's feet (P = 0.0111) and in the Global Aesthetic Improvement Scale. (P = 0.0033). The adverse events found were pain, inflammation and ecchymosis. The degree of satisfaction reported by the patients was good (16.6%) and very good (83.3%) (P = 0.0021).
Conclusions: The autologous platelet concentrate proved to be effective and safe in reducing the signs of cutaneous aging of crow's feet, associated with a high degree of patient satisfaction.
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