Authors: Mamaev NN, Shakirova AI, Kanunnikov MM, Gindina TL.
A new concept of acute myeloid leukemia (AML) relapses is proposed which is linked with direct participation of BAALC-expressing earlier leukemic progenitors (ELP). The latter may be studied effectively by means of real-time quantitative polymerase chain reaction (RT-qPCR). Recent findings in support of this conception and ongoing prospective studies in the field are shortly discussed.
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