International Journal of Biomedical Research & Practice

Open Access ISSN: 2769-6294

Abstract


Dosimetry Approach of Coronavirus

Authors: Scarlat F, Stancu E, Scarisoreanu A.

The human body is exposed to external ionizing radiation when the source of radiation is outside the body and to internal radiation when the source of radiation is inside the body. The energy absorbed by the ionizing radiation per unit mass (J / kg) represents the absorbed dose (Gy) in the target organ, T. Depending on the radiation quality, the relative biological efficacy, in the same target; the dose becomes the equivalent dose, HT (Sv), in organ T. This is multiplied by the organ weighting factors (wT ), ie the ratio between the risk coefficients for the organs or tissues, RT , and the total risk coefficient (R = ∑ RT ), then the sum (∑wT HT ), represents the effective dose E (Sv). Adverse health effects due to radiation exposure are deterministic at high doses, with threshold, and stochastic type, at low dose and rate, without threshold, below 100 mSv. Dosimetric and epidemiological studies on these effects have shown a linear relationship between dose (Gy) and the probability of incurring of stochastic effects (cancer and hereditary effects). In the case of radon daughter external exposure and in workplaces other than mines, the linear relationship is between the mortality rate due to inhalation of radioactive aerosols and radon exposure (mJ h m-3). The conversion from exposure (WLM) to effective dose (Sv) was based on equal detriment, not on dosimetry. Regarding the mode of action of SARS Cov-2 virus (100-150) nm, given that they can only grow in living cells, (50- 100) µm, it follows that the life cycle of a virus has two distinct stages. In the first stage, the virus appears outside the cells in the form of a neutral virus particle as a passive transport vehicle, which provides opportunities for the infection to spread both from cell to cell within the multicellular organism and between individuals. In the second stage, the virus is inside the infected cell (50 µm, 10-9 g), where the replication and directing of processes in the host cell to the synthesis of new infectious virus particles takes place. Other building blocks for the virus particle, such as the energy required and the main mechanisms for assembling a virus are provided by the infected cell. Starting from the radon conversion convention, in this paper, it is proposed, as exposure, the photon field fluence rate Φ, (photons/cm2 .s), as being equal to the rate fluence of the field SARS Cov-2, φ (coronavirus-particles/cm2 .s), and their report will be finalized by radiobiological and epidemiological studies to determine the number and energy of the photon that will be equivalent to the Coronavirus particle.

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