Authors: Ran Chu, Zhongping Cao.
Background: Volume therapy is important to keep the graft kidney function and organ perfusion during kidney transplantation, and almost all patients undergo dialysis before operation. The study is designed to show whether the dialysis volume is more closely associated with the total fluid infused during renal transplantation.
Methods: Thirty patients undergoing kidney transplantation were included. The dialysis volume was recorded just before operation. Stroke volume variation (SVV) was kept under 13, and central venous pressure (CVP) was kept between 8 to 12 mmHg before the reperfusion of the graft kidney until the end of the operation. The total fluid infused was recorded at the end of the operation.
Results: All patients included in the study underwent successful renal transplantation and recovered to normal after operation. The MAP, CVP, CO before graft renal reperfusion and 30 minutes after reperfusion increased significantly than that of after anesthesia, while SVV before graft renal reperfusion and 30 minutes after reperfusion decreased significantly than that of after anesthesia. The total fluid infused was significantly different from the dialysis volume, and was not correlated with the dialysis volume.
Conclusions: These data suggested that fluid therapy is necessary to the recovery of graft renal function, and that the dialysis volume, as part of the volume lost before operation, cannot be used to assess the need of total fluid infusion.