Authors: Kone Djakaridja, Yeo Liomehin, Coulibaly Dramane, Kadiane-Oussou Juliette, Dje Bi Hospice, Yapo Martine Tatiana, Karidioula Jean-Marie, Aba Yapo Thomas, Kra Ouffoue.
Introduction: TB/HIV co-infection is a major health problem in Africa. This co-infection is associated with high mortality and additional therapeutic challenges. This study aimed to determine current aspects of tuberculosis in TB/HIV patients.
Materials and method: We carried out a retrospective, descriptive and analytical study over a period of 4 years. We used the medical records of TB/HIV patients from the Gbêkê region. Data analysis was performed with Epi Info 3.2.1 software.
Results: The prevalence of HIV in tuberculosis patients was 18.7%. The average age of the patients was 37 years old. The female gender (60%) predominated. The patients lived as a couple in 49.1%. Nurses accounted for 2.6%. Pulmonary tuberculosis (79.3%) was predominant. The extra-pulmonary forms were dominated by pleural (45.3%) and lymph node (32.4%) tuberculosis. The site of infection was unique (74.4%) and drug-resistant forms accounted for 3.1%. All the patients screened were immediately put on anti-tuberculosis treatment, only 94.8% had been put on antiretroviral treatment. Mortality was 18.7%. The determinants of mortality were the age group from 5 to 14 years (p<0.001), female gender (p=0.04), civil servant patients (p<0.001), patients without profession (p<0.001), pleural tuberculosis (p= 0.04) and neuromeningeal tuberculosis (p=0.011).
Conclusion: Prevalence and mortality remain high in TB/HIV patients. Tuberculosis was more deadly in adolescents, women, civil servants, the unemployed, the pleural and neuromeningeal form.
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