Recent Advances in Clinical Trials

Open Access ISSN: 2771-9057

Abstract


Lipid Emulsion for Spinal Anaesthesia Reversal - A Therapeutic Option

Authors: Hadbi Mohamed, Benalakma Dalila, Bennamane R, Fellah Nadia.

High spinal anaesthesia is also one of the commonly faced problems, with a low incidence of a complete spinal block; which is one of the life-threatening complications unless immediately identified and treated. Up to now, its management has relied mainly on intensive means such as respiratory and circulatory assistance.

Intravenous lipid emulsions have an established position in the management of local anesthetic toxicity. After the success in this area, ILE has been used under clinical conditions for various kinds of overdose. At present, ILEs are expanding into a new field, that of reversing the effects of local anesthesia on peripheral nerves and neuraxial anesthesia.

We report two cases of patients operated at our department, the first for genital prolapse under perimedullary anaesthesia, complicated by high spinal anaesthesia. The second case was a patient who underwent Caesarean section under spinal anaesthesia, intubated mid-operatively and presented with postoperative delayed awakening. Both complications were resolved by intralipid injection.

We then reviewed the literature concerning similar cases and the different means used to resolve the problem.

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