Authors: Heather A. Domby, Mohammed S Inayat, Vincent S. Gallicchio
Characterized by the progressive loss of dopaminergic neurons in the brain, Parkinson’s disease (PD) is a relatively common neurodegenerative disorder that affects millions worldwide. PD leads to the gradual manifestation of motor symptoms, including tremors, rigidity, and bradykinesia, as well as non-motor symptoms, such as mood disruption and cognitive impairment. These symptoms can significantly reduce an individual’s quality of life, yet it is essential to note that the progression of PD is highly variable amongst those affected. There is currently no cure for PD; thus, the need for research surrounding improved symptomatic treatments, disease-modifying therapies, and biomarker identification is crucial. This review addresses the use of stem cell therapy as a promising avenue in combating the challenges posed by PD and provides insight into a recent Parkinson’s biomarker study sponsored by The Michael J. Fox Foundation for Parkinson’s Research (MJFF).
View/Download pdf