Introduction: Meningiomas are the most common primary tumors of the central nervous system, accounting for approximately one third of all intracranial neoplams. The aim of this study was to describe the epidemiological and histopathological characteristics of meningiomas diagnosed at the Pathology Departement of the Soavinandriana Hospital Center (CENHOSOA), Antananarivo Madagascar.

Patients and Methods: A retrospective, descriptive, and analytical single-center study was conducted in the Pathology Department of CENHOSOA, Antananarivo, Madagascar, over a 10-year period from January 2013 to December 2022. All histologically confirmed cases of meningioma were included.

Results: During the study period, 38 cases were collected. The mean age of patients was 48.9 ± 14.6 years, with a female predominance (sex ratio: 2.1). Signs of intracranial hypertension were the most common presenting symptoms, occurring in 28.4% of cases. The convexity was the most frequent tumor location (65.8%). According to the WHO classification, grade I meningiomas represented 81.8% of cases, with the meningothelial subtype being the most prevalent histological variant (52.6%). Surgical specimens accounted for 94.7% of the analyzed samples.

Conclusion: Meningiomas predominantly affected middle-aged adults and were mainly represented by WHO grade I tumors. A multicenter study would provide a more comprehensive overview of the epidemiological, clinical, and histopathological profile of meningiomas in Madagascar