Cancer Science & Research

Cancer Science & Research

Open Access
ISSN: 2639-8478
Review Article

The Role of Mutations Genes NPM1, FLT3, DNMT3A, CEBPA, IDH1& IDH2 in Cytogenetically Normal Acute Myeloid Leukemia

Authors: Saeed Heidarisani, Mohammad Yazdani, Hediyeh Hosseini, Shahin Asadi.

DOI: 10.33425/2639-8478.1092


Abstract

Cytogenetically normal acute myeloid leukemia (CN-AML) is a type of hematopoietic tissue (bone marrow) cancer called acute myeloid leukemia. In normal bone marrow, early blood cells called hematopoietic stem cells develop into several types of blood cells: white blood cells (leukocytes) that protect the body against infection, red blood cells (erythrocytes) that carry oxygen and platelets (thrombocytes) play a role in blood coagulation, in acute myeloid leukemia, the bone marrow produces a large number of abnormal and immature white blood cells called myeloid blasts. Instead of becoming normal white blood cells, myeloid blasts turn into blood cancer cells.

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Citation: Saeed Heidarisani, Mohammad Yazdani, Hediyeh Hosseini, et al. The Role of Mutations Genes NPM1, FLT3, DNMT3A, CEBPA, IDH1& IDH2 in Cytogenetically Normal Acute Myeloid Leukemia. 2022; 5(3). DOI: 10.33425/2639-8478.1092
Editor-in-Chief
Lee Guek Eng
Lee Guek Eng
Department of Medical Oncology | National University of Singapore

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Journal Metrics
Impact Factor 2.4*
Acceptance Rate 75%
Time to first decision 6-10 Days
Submission to acceptance 12-15 Days