Cancer Science & Research
Open Access
ISSN: 2639-8478
Research Article
View / Download PDF
Vitamin B12 Supplementation and Treatment in Cancer Patients: A Narrative Review
Authors: Emmanuel Andres, Noel Lorenzo-Villalba.
Abstract
Vitamin B?? (cobalamin) deficiency is frequent in oncology, resulting from nutritional deficits, malabsorption, drug interactions, and tumor-related mechanisms. Correction of deficiency is crucial to prevent hematologic, neurologic, and nutritional complications and to optimize tolerance to chemotherapy, especially antifolates such as pemetrexed. This review summarizes recent evidence on the prevalence, mechanisms, diagnosis, and clinical management of vitamin B?? deficiency in cancer patients, including supplementation strategies and safety considerations.
Citation:
Emmanuel Andres, Noel Lorenzo-Villalba. Vitamin B12 Supplementation and Treatment in Cancer Patients: A Narrative Review. 2026; 9(1).
DOI:
10.33425/2639-8478.1118
Editor-in-Chief
Lee Guek Eng
Department of Medical Oncology | National University of Singapore
View full editorial board →
Journal Metrics
Impact Factor
2.4*
Acceptance Rate
75%
Time to first decision
6-10 Days
Submission to acceptance
12-15 Days