Introduction: Coronary angiography and percutaneous coronary angioplasty have revolutionized the management of coronary diseases, thereby reducing their morbidity and mortality. However, they carry risks and complications that are poorly documented in Sub-Saharan Africa, particularly in Mali, which is why this study aimed to evaluate these complications.

Patients and Methods: We conducted a cross-sectional, descriptive study lasting 3 years and 7 months at the CHU Mère-Enfant le Luxembourg in Bamako, including all complications during coronary angiography and/or coronary angioplasty procedures.

Results: We collected 40 cases out of 1,397 procedures, representing a frequency of 2.9%. The average age was 59.93, with a slight male predominance. Most patients were admitted for ACS. Classic cardiovascular risk factors were mainly hypertension (62.5%) and diabetes (50%). Several patients (46.2%) had left ventricular systolic dysfunction. Percutaneous coronary angioplasty was the most commonly performed procedure (87.5%), mainly via 6F radial access. Multi-vessel disease predominated, and the LAD was affected in 65.7% of cases. All angioplasties were successfully performed with 100% drug-eluting stent placement. Complications were mainly hematomas at the puncture site. Rare complications observed included compartment syndrome, cardiac arrest, stroke, mechanical complications, renal failure, and early stent thrombosis. The outcome was favorable in the majority of cases (82.5%).