Case Report

Concurrent Deep T-Wave Inversions and QT Prolongation with Azithromycin Treatment

Authors: Melissa Wasilewski, Sara Kwiatkowski, Kunal Kapoor, Sumon Roy.

DOI: 10.33425/2639-8486.1135

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Abstract

The tendency of macrolide antibiotics to prolong the QT interval in certain patient populations is well documented. In contrast, limited reports exist of medication-induced deep T-wave inversions. We recently encountered a case of azithromycin-induced QT prolongation with concurrent deep TWI, an association that is rarely observed in clinical practice. As similar ECG changes can be seen with life-threatening conditions such as coronary ischemia and cerebral hemorrhage, comprehensive workup to rule out acute pathologies is critical when this pattern is recognized.

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