Chemical & Pharmaceutical Research
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ISSN: 2689-1050
Research Article
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Synthesis, Structural Characterization and In Vitro Leishmanicide and Antifungal Activities Studies of Schiff Base Compounds
Authors: Kangah Niameke Jean-Baptiste, Tuo Nanou Tieba, Ziale Djele Alette Edwige, Kablan Ahmont Landry Claude, Kodjo Charles Guillaume, Ziao Nahosse.
Abstract
N, N'-bis (2-nitrophenyl methylene)hexane-1,6-diamine, N, N'-bis (4- nitrophenylmethylene)benzene-1,3-diamine, N, N'-bis (p-nitrophenylmethylene) cyclohexane- 1,2-diamine were synthesize and have been characterized by conventional spectrometry methods (NMR, IR and HR-ESI-MS). Antileishmanicide and antifungal screening showed that, N, N'-bis (2-nitrophenyl methylene) hexane- 1,6-diamine, with MIC of 16.40 mg/L and 125 mg /L respectively, is the most active.
Citation:
Kangah Niameke Jean-Baptiste, Tuo Nanou Tieba, Ziale Djele Alette Edwige, et al. Synthesis, Structural Characterization and In Vitro Leishmanicide and Antifungal Activities Studies of Schiff Base Compounds. 2024; 6(2).
DOI:
10.33425/2689-1050.1062
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Yousra A. R. Nomier
College of Pharmacy | Jazan University
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