Research Article

Effect of Malaria Infection in Pregnancy on Some Inflammatory and Haematological Indices at Nnamdi Azikiwe University Teaching Hospital, Nnewi

Authors: Ifeanyichukwu MO, Okezie BN, Obi E.

DOI: 10.33425/2639-8494.1023

---

Abstract

This study was carried out to determine the effect of malaria infection in pregnancy on some inflammatory and haematological indices. It was carried out at the ante natal clinic of Nnamdi Azikiwe University Teaching Hospital, Nnewi. Two hundred and sixty two subjects were recruited comprising: Two hundred and six pregnant women who tested positive to malaria infection and fifty-six who tested negative to malaria infection. C-reactive (CRP), Complements 3 and 4 (C3 and C4), were determined using turbidimetric method, haematological parameters were done using automation method and malaria infection was determined using Giemsa staining technique. Pearson correlation was used to test for relations while Student t-Test and Analysis of Variance (ANOVA) were used to analyze significance of differences in mean values between groups and among groups respectively. The C3 and C4 were significantly reduced in pregnant women infected with malaria parasite when compared with control (P0.05 in each case). However, C4 was significantly reduced in pregnant women with malaria infection in their first and third trimesters when compared with the second trimesters (P

View / Download PDF