Research Article

Hematological Profile of Patients with Hepatitis B Aged 18 To 60 Years

Authors: Tariam Djibangar Agnès, Mayanna Habkreo, Adil Abdraman Madary Ourbo, Mahamat Issa Gnoroty, Abdelaziz Abdelkerim, Ousman Fager Malick, Nonhoungar Rodrigue, Doudje Kondy, Bessimbaye Nadlaou, Abdelsalam Tidjani.

DOI: 10.33425/2639-8494.1065

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Abstract

Hepatitis B is a diffuse liver disease characterized by inflammatory hepatocellular damage and degenerative hepatocyte alterations, such as cytolysis, fibrosis, and necrosis. It evolves in acute or chronic forms with clinical manifestations linked to immune mechanisms. The present study aimed to analyze the hematological profile of adult hepatitis B patients.

Materials and Methods: This was a cross-sectional descriptive study conducted on 43 hepatitis B-positive patients at the CHU-RN from March to May 2024 (a 3-month period). Blood samples were collected from the elbow crease in EDTA tubes for complete blood count (CBC) analysis using an automated analyzer.

Results: The study revealed that the age group 18–29 years was the most represented, with 19 patients (44.2%), predominantly male (67.4%). Urban areas accounted for 60.5% of the patients (26 individuals). Variable anemia, progressing toward chronicity, was observed among the patients.

Conclusion: Hepatitis B reflects cirrhotic and hepatocellular complications. Prevention is essential to maintain health and well-being.

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