Clinical Immunology & Research
Open AccessPrevalence and risk factors of malaria among children under five years in High and Low altitude rural communities in the Hohoe Municipality of Ghana
Authors: Margaret Kweku, Wisdom Takramah, Wisdom Kudzo Axame, Richard Owusu, Mohammed Takase, Martin Adjuik, Elvis Tarkang.
Abstract
Background: Malaria due to P. falciparum remains one of the most important causes of morbidity and early mortality in endemic regions of sub-Saharan Africa. This study assessed the prevalence of malaria among children less than five years residing in High-Altitude and Low-Altitude rural communities in the Hohoe municipality.
Methods: A community-based cross-sectional survey involving children less than five years in four selected rural communities. Information was collected on the background of the children, ownership and use of LLIN and fever. Anthropometric indices and axillary temperature were measured, as well as RDT and blood film for malaria parasites and haemoglobin levels. Proportions were analyzed using Chi-square and Multivariable logistic regression was used to determine the association between dependent and independent variables.
Results: A total of 325 children with 174 (53.5%) from Low-Altitude and 151(46.5%) from High-Altitude communities were surveyed. The prevalence of malaria among Low-Altitude and High-Altitude children as indicated by RDT was 56.9% and 19.9% respectively and by microscopy was 41.4% and 3.3% respectively. Ownership and use of LLIN among Low-Altitude and High-Altitude children were high and similar (96.6% vs. 97.4%) and (79.9% vs. 75.5%) respectively. High-Altitude children were 96% less likely to have malaria as compared to Low-Altitude (AOR=0.04, p
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