Clinical Reviews & Cases

Clinical Reviews & Cases

Open Access
ISSN: 2689-1069
Case Report

Transitory Polyglobulia and Low Platelet Count Associated With Pfizer/ Biontech Mrna Vaccine - A Case Report

Authors: Suchmacher Mendel, Geller Mauro.

DOI: 10.33425/2689-1069.1060


Abstract

The authors report a case of transitory polyglobulia and low platelet count associated with Pfizer mRNA vaccine administration. Upregulation of heme, beta- and gamma-globin synthesis due to activation of NFR2 by IRP/ synthetic mRNA/eIF4E complex and decreased immune-mediated megakaryocytopoiesis and/or peripheral platelet destruction, were hypothesized mechanisms.

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Citation: Suchmacher Mendel,  Geller Mauro. Transitory Polyglobulia and Low Platelet Count Associated With Pfizer/ Biontech Mrna Vaccine - A Case Report. 2023; 5(4). DOI: 10.33425/2689-1069.1060
Editor-in-Chief
Roy G. Beran
Roy G. Beran
Department of Medicine | University of New South Wales

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