Dermatology Research
Open AccessPathological Co-localization of Lichen Planopilaris and Folliculitis Decalvans with Clinical Manifestations of LPP only
Authors: Ramina Mofarrah, Ramin Mofarrah, Masoud Farinam, Mohammad Sajad Sadeghpoor.
Abstract
Cicatricial alopecias are categorized based on their immune cell infiltration with Lichenplanopilaris (LPP) predominantly showing lymphocytic infiltration and folliculitis decalvans (FD) presenting with neutrophilic infiltration. Case series have been reported in previous literature introducing a concomitant or sequential occurrence of both diseases known as folliculitis decalvans lichen planopilaris spectrum (FDLPPS). In all these studies, concomitant cases presented with both clinical and histopathological features of FD and LPP, while sequential cases showed a precedence of FD with over time transition to LPP both clinically and histologically. This raised a discussion over the importance of the correct diagnosis and treatment in cicatricial alopecias, particularly in cases who’s clinical and trichoscopic signs can’t be fully attributed to one disease only, or cases of FD that prove unresponsive to treatment over time. We aim to present a rare case in this spectrum, that doesn’t fall into any of the categories reported previously. Our patient manifested clinical signs of LPP only while showing histopathological features of LPP and FD simultaneously. It seems that this case is showing a precedence of clinical LPP over FD unlike other literature, while presenting with a concomitant occurrence of histopathological signs. Based on these findings, it was decided by the authors to treat the patient for both types of cicatricial alopecias simultaneously.
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