Introduction: Irritable Bowel Syndrome (IBS) is a common functional gastrointestinal disorder, with a significant impact on quality of life, particularly among young adults. The objective was to determine the prevalence and associated factors of IBS among students at Université des Montagnes (UdM), Cameroon.

Methods: A cross-sectional study was conducted from February to May 2024 among 450 students from the Banekane campus, UdM. The sampling method used was cluster sampling. The diagnosis of IBS was based on the Rome IV criteria. Data analysis was performed using SPSS 20.0 software. Associated factors were identified by multivariate logistic regression (p < 0.05).

Results: The prevalence of IBS was 17.6%. The IBS-C subtype was predominant (44%). Factors significantly associated with IBS included: regular alcohol consumption (OR = 1.79; 95% CI [1.08-2.9], p = 0.02), magnesium-rich diet (OR = 1.64; 95% CI [1-2.69], p = 0.049), probiotics (OR = 6.64; 95% CI [2.81-15.68], p < 0.001), and soluble fiber intake (OR = 1.46; 95% CI [1-2.69], p = 0.049).

Conclusion: IBS is common among UdM students. Specific diet and consumption habits may influence its onset. Nutritional awareness and early management are necessary