The following is a case report of a 17-year-old immunocompetent female with no significant past medical history, who presented to King Fahad Hospital after multiple previous hospital visits. She was complaining of unexplained abdominal pain, fever, weight loss, and diarrhea. Initial investigations raised concerns about colon malignancy or inflammatory bowel disease. However, further evaluation, including endoscopy and biopsy, revealed the diagnosis of gastrointestinal basidiobolomycosis through histopathological study. Treatment with antifungals started for 6 months, and the patient showed remarkable improvement during clinical stay and follow-up.