Introduction: Maternal mortality remains a major public health problem in Africa and in Chad in particular. This study aims to contribute to the reduction of maternal deaths in N’Djamena Mother and Child University hospital (NMCUH).

Patients and Methods: This was a retrospective, descriptive and analytical study lasting 18 months from January 2021 to June 2022. All patients who died during pregnancy, delivery, postabortion or postpartum were included. The variables studied were epidemiological, clinical and therapeutic. The data collected were analysed using SPSS 18.0 software. The Chi² test was used to compare two variables with a significant threshold p value ? 0.05.

Results: We collected 124 deaths out of 14996 admissions, a frequency of 0.82%. These deaths mainly affected women aged 30-34 years, grand multiparous (79%), married (95.2%), not followed up (58.9%), referred (59.7%). The causes of death were dominated by hemorrhage (42.7%), infection (31.5%) and malaria (55.6%). Deaths were recorded within 24 hours of admission (54.8%) and postpartum (66.1%). The first delay (67.7%), and the delay in consenting to surgery (55.3%) were more common.

Conclusion: The frequency of maternal deaths remains high at the NMCUH. Enormous efforts remain to be made by acting on the different factors in order to reduce maternal mortality.