Cancer recurrence is a decisive turning point in the disease, from which the patient's physical condition declines. The prognosis of the patients depends to the time of its occurrence and its location.

Patients and Methods: From 2013 to 2016, we collected 49 cases of patients treated for locally advanced breast cancer and documented recurrence. The data were collected from the computerized continuous monitoring records using the Filemaker software and then analyzed with the SPSS software.

Results: The average age of patients at diagnosis was 41 years. More than half of our patients (51%) had a body mass index (BMI) greater than or equal to 25. The average consultation time at the center after the tumor’s discovery was 9.4 months. The mean size of the breast tumor was 55.2 mm, 63% at the T3 stage, 18.4% at the T4d stage, 10.2% at the T2 stage and 8.2% at the T4b stage. Hormone receptors were negative in 40% and tumors did not overexpress the HER-2 oncoprotein in 55.1%. Only 14.2% of our patients received hormonal therapy. The surgery was radical in 95.9% of the cases. Recurrence occurred on average after 18 months after treatment and overall survival was 23.5 months. The outcome was fatal for 35 patients (71.4%).

Conclusion: Breast cancer is in the process of becoming the first woman cancer in Senegal as in many other developing countries and is increasingly interested in the useful portion of society due to the young age of the patients. Steps must be taken to improve the quality and duration of their survival.