Gestational Trophoblastic Disease (GTD) is characterized by an abnormal proliferation of trophoblastic cells that encompasses a group of distinct pathologies. Choriocarcinoma (CC) is a malignant neoplasm whose pathogenesis is based on abnormalities in the regulation of trophoblast cell invasion in the decidua. It has varied manifestations and its recognition becomes even more difficult when a hydatidiform mole, as in the patient in question, does not precede it. Among the risk factors for the development of CHD, an episode of miscarriage, multiple pregnancy, nulliparity or patients over 35 years of age stand out. The vast majority of primary CC lesions affect the uterus, with primarily extrauterine lesions being a rarity. Thus, its association with ectopic pregnancy is extremely rare and aggressive. For this reason, the present study aims to report the case of a choriocarcinoma in an ectopic pregnancy in the fallopian tube.