Gynecology & Reproductive Health
Open AccessComparison of Endoglin Levels (CD 105) in Women's Menstrual Blood Endometriosis and without Endometriosis
Authors: Jeimmy Mangalonggak, Nasruddin Andi Mappaware, St. Maisuri T. Chalid, John Rambulangi, Sharvianty Arifuddin
Abstract
Aimed: To evaluate menstrual blood endoglin levels between women with endometriosis and without endometriosis.
Methods: A cross-sectional study was performed on 52 eligible women. Endometriosis was confirmed with laparoscopy or laparotomy. Menstrual blood collected in the first or the third day of menstrual cycle using a menstrual cup. Endoglin levels from menstrual blood serum were measured with the ELISA method.
Results: Menstrual blood endoglin levels in mild endometriosis were significantly higher compared with control (22.903 pg/ml vs 5.250 pg/ml; p<0.05) as well as the endoglin levels between severe endometriosis compared with mild endometriosis showed endoglin levels significantly higher in severe endometriosis (31.957 pg/ml vs. 22.903 pg/ml; p<0.05).
Conclusion: Menstrual blood endoglin levels positively correlated with endometriosis stage.
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