Goal: To describe the prevalence of a successful fertilization and pregnancy rate, and the influence of different factors in couples who undergo homologous artificial insemination.

Material and Methods: Retrospective cohort study, in patients with infertility that underwent a homologous artificial insemination procedure at the Fertility Clinic in Santa Rosa de Lima Hospital, Ensenada, Baja California, Mexico. Failure in achieving fertilization and pregnancy was associated to the presence of infertility factors from different origins: cervical factors, uterine, fallopian tube and peritoneum, endocrine-ovarian, masculine, or a combination of them. Measures of association were calculated and logistic regression was used to adjust for age and body mass index.

Results: 151 patients were studied. From all successful pregnancy cases, 63 were achieved in the first insemination cycle (17.9%), 35 in the second cycle (27.8%), 29 in the third cycle (36%) and 24 in the fourth cycle (42.8%). The uterine factor was strongly associated to failure in achieving pregnancy (OR 5.98, 95% CI 1.82-19.62), followed by the cervical factor (OR 3.52, 95% CI 1.35-9.15). The rest of the factors were not significantly associated to failure in achieving pregnancy.

Conclusion: Homologous artificial insemination.