Introduction: Sexual assaults are a major public health and medico-legal concern in Senegal, mainly affecting women and minors.

Objective: To describe the epidemiological, clinical, and medico-legal characteristics of sexual assaults managed in a regional hospital in Senegal. Methods: This was a retrospective, descriptive, single-center study conducted from January 1, 2016, to June 30, 2025, including all female patients admitted for suspected sexual assault. Data were collected from medical records and analyzed using Microsoft Excel 2016.

Results: Out of 18,000 gynecological consultations, 24 cases of sexual assault were recorded (0.13%). The mean age of victims was 12 years (range: 7 months–19 years), with 87.5% being minors. Most were single (92%) and in school (66.6%). The perpetrator was known in 54.2% of cases, most often a neighbor (45.8%). The family home was the main site of the assault (25%). Penile-vaginal penetration occurred in 54.2% of cases. Genito-anal lesions were observed in 66.7% of victims. Biological tests were performed in 12.5%, HIV post-exposure prophylaxis was prescribed in 8.3%, and psychological care was provided in one case only.

Conclusion: Sexual assaults in Senegal mainly affect young female minors. Medico-legal and psychological management remains inadequate. The establishment of regional medico-legal units and improved coordination between health and justice sectors are essential.