International Journal of General Clinical Case Reports
Open AccessKawasaki Disease in Children; Clinical Manifestations, Risk Factors and Prognosis, a case Series and Review of the Literature
Authors: Parichehr Tootoonchi.
DOI: -
Abstract
Background: Kawasaki disease (KD) is a vasculitis involved small and medium sized arteries and usually is a benign self-limited disease. KD usually presented with fever for 5 days or more with rash, non- exudative conjunctivitis, edema or erythema of hands and feet, unilateral lymphadenopathy or mucosal involvement. If 4 or 5 of the above clinical manifestations are present, the KD is categorized in classic type. Less than 4 above clinical signs categorized as incomplete or non-classic KD.
Materials & Methods: In this case study, all of the patients admitted with KD included. In all the patients, data about cases’ age, sex, fever duration, hospitalization duration, clinical manifestations associated with Fever, the day of stopping fever following the IVIG treatment, second week’s platelet count, the time of the patient’s CRP or platelet count became normal, and the result of base line and follow ups echocardiography were gathered.
Results: 20 cases with KD included in this case study. 75% of the cases were male. The age range of the cases was 13-108 months. The cases mostly presented in winter (11 cases, 55%) or spring (4 cases, 20%). Most of the cases presented as incomplete KD (IKD) (13 cases, 65%). 3 cases have shown abnormal base-line echocardiography at admission day. All the cases with abnormal echo- cardiography presented as diffuse ectasia. No case of aneurysm, thrombosis or occlusion in coronary arteries has detected in the baseline or follow ups echocardiography in the 3 cases or other cases.
Conclusion: Although some of our results are like the findings of other studies, designing and performing large multicenter prospective studies is recommended.
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