It is estimated that 8 to 15% of university students have some psychiatric disorder during their academic career, especially depressive and anxiety disorders. This is aggravated in the Amazon region as the socioeconomic level is one of the most relevant predictors of well-being and mental health. In this work we investigate the socioeconomic and mental health factors that impact academic learning process. For this, tests were applied to assess cognition (through the mini mental state examination-MMSE), psychic state (through the HAD scale, Beck's depression inventory - BDI and suicide risk index -SRI) as well as assessing the student's social and family situation (through family APGAR) within a period of one year. The results of these tests will be related to the student's performance coefficient (CR), which refers to a number (from 0 to 10) that corresponds to the student's academic performance
at the institution. It was observed that 67% of the sample showed decreased cognition according to MMSE, predominantly female, almost half of the sample (49%) presented anxiety, according to HAD, 100% of students with severe depression in BDI also showed anxiety in HAD and 59% of students with severe depression in BDI the risk of suicide was high according to SRI. In addition, there is no relationship between mental disorders and academic performance in these students.