Pharmacology has risen to a new horizon with its many branches of clinical research and practices. One among these is the field of neuro-psycho-pharmacology. Neuroscience is the study incorporating the brain, nerves and vessels within. The brain is truly an amazing organ with many complex features and interesting feeds, which focus on many areas of expertise such as learning & cognitive developments, motor movements and many other various capabilities, which are yet to be understood. Combining the knowledge acquired through neuroscience, enabled scientists and researchers alike to understand behavioural and molecular aspect studies into one category known as psychology. This then helped scientists and pharmaceutical companies alike to research and develop drugs that could assist in conditions such as chronic depression, anxiety and various other psychotic disorders incapacitating the core cognitive developments of the brain and its associated nerves and blood vessels. This review thereby focuses on the adverse effects caused by excess consumption of certain drugs due to addictive tendencies and how this leads to impairment of cognitive behaviour.