Trauma in childhood is a grave medical and psychosocial problem. This kind of trauma occurs when a child experiences several traumatic events at an early age. Early childhood trauma disrupts the normal neurological process of the body which subsequently hinders the normal development of the brain. In recent years, a growing body of research has emerged linking childhood trauma to an increased risk of developing various chronic diseases, including cardiovascular, diabetes, pulmonary, and cancer. This paper aims to review and synthesize the current literature on the negative impacts of childhood trauma including drug abuse, sex addiction, depression, and other psychiatric problems. The findings suggest that exposure to childhood trauma significantly increases the risks of developing drug abuse, sex addiction, depression, anxiety, and many other chronic diseases. The findings highlight the urgent need for early recognition and intervention in childhood trauma to potentially alleviate its harmful consequences in adulthood.