Introduction: Neurological diseases are defined by lesional damage to the brain, spinal cord, peripheral nerves or muscles. They are multiple and varied.

Objective: Determine the profile demographic, clinical and evolution of patients hospitalized in the neurology unit of the John Paul II hospital.

Material and Methods: This was a prospective descriptive study lasting 1 year carried out at the Neurology unit of the Jean Paul II hospital, in the suburbs of the capital Conakry. All medical records were reviewed by a neurologist and neurological diagnoses classified according to ICD-10.

Results: Out of 215 patients received, 182 (84.7%) received a neurological diagnosis. The average age of the patients was 57.7 ± 17.1 years with a male predominance of 53.4%. The most frequent reasons for consultations were motor deficit (85.16%) and language disorders ( 58.24 %). According to the ICD-10 classification, episodic and paroxysmal disorders (EME, epilepsy, cerebrovascular disorders) were observed in 82% of patients, followed by inflammatory diseases of the central nervous system in 7.3% of patients.

Conclusion: Neurological pathologies constitute a major public health problem and represent the leading cause of years lived with disability worldwide.