Background: The issue of cancer is a global concern, and in the year 2022, one out of every six human deaths was attributed to cancer. This study aims to evaluate the demographic characteristics, institutional incidence and mortality rate of different cancers at the RRivers State University Teaching Hospital (RSUTH).

Materials and Methods: A retrospective observational study was carried out among all patients diagnosed with cancer at the RSUTH between January 2021 to December 2024, using data obtained from the Cancer Registry and other Departments of the hospital. Data collected were organized into tables and expressed as rates, ratios, and percentages.

Results: Patients ranged in age between 20-90 years was observed, and most cancers were at the peak age between 40 and 59 years, especially for the most common cancers – breast and prostate. The incidence rate for cancers in year 2024 Int J Res Oncol, 2026 Volume 5 | Issue 2 | 2 of 10 were as follows: breast cancer was 120.67/100,000, prostate cancer was 85.47/100,000, cervical cancer = 19.11/100,000, endometrial cancer = 14.08/100,000, skin cancers = 14.08/100,000, and others. The cancers with high institutional mortality rates were breast cancer (33.18/100,000), prostate cancer, ovarian cancer (7.04/100,000), etc. Cancer mortality to incidence ratios in ascending order: prostate cancer (0.04), cervical cancer (0.11), etc.

Conclusion: A wide range of cancers were reported, and the cancers with high incidence rates were breast cancer, prostate cancer, cervical cancer, endometrial cancer, skin cancers, colorectal cancer, ovarian tumors. The institutional cancer mortality rates were derived, and the high mortality cancers were breast cancer, prostate cancer, ovarian cancer, endometrial cancer. Cancer mortality to incidence ratios were found to be relatively higher than observed global findings.