Endovascular interventions have recently become the first-line treatment for arterial diseases (AD). However, there is no consensus yet on the primary endovascular method. Intensive studies carried out in recent years have been aimed not only at the treatment of existing stenosis but also at preventing the narrowing problem. Drug-eluting balloons (DEB) have recently become a new alternative treatment in this context. DEB allows the release of antiproliferative drug into the stenosis area without leaving any stent strut. It increases the therapeutic effect by preventing intimal proliferation and restenosis. Available data show that DEB has satisfactory efficacy and low risk, is superior to BMS and is noninferior to DES. It may be a suitable alternative for preventing coronary and peripheral artery diseases and in-stent stenosis.

This article aims to review current data on the use of DEB in arterial diseases.