Objective: This study aims to evaluate the levels of lipid profile parameters in Chronic Renal Failure patients on Maintenance hemodialysis and to compare its level with age matched healthy control population.

Method: Cross sectional study involving 262 Individuals between the age 46 -75 years in the population of Bengaluru, India between February 2022 to May 2023. Venous blood was collected from 131 CRF patients on MHD and from 131 healthy individuals and analyzed for lipid profile parameters TC, TG, VLDL,LDL,HDL.and urea,creatinine.

Results: In MHD patients, serum TG and VLDL levels were found to be significantly elevated compared to healthy control population. HDL was significantly reduced compared to control healthy population. There was no significant change in the levels of TC and LDL.

Conclusion: Frequent monitoring of these lipid profile parameters may help in better treatment, hence itmay reduce the morbidity and mortality of Patients on MHD.