The parapharyngeal space (PPS) is a deep anatomical region that may harbor a broad range of pathological entities; however, tumors in this location are uncommon. Pleomorphic adenoma is the most prevalent benign salivary gland neoplasm but is infrequently encountered within the PPS. This report presents two cases of large pleomorphic adenomas arising in the PPS, both presenting with progressive oropharyngeal or cervical swelling.

A detailed preoperative assessment, including contract-enhanced computed tomography and fine-needle aspiration cytology, was performed to evaluate tumor extent and characteristics. Both patients underwent complete surgical excision using a transcervical submandibular approach without mandibular osteotomy. Histopathological findings confirmed pleomorphic adenoma in both cases.
These cases highlight that a transcervical submandibular approach without mandibular splitting can provide sufficient exposure for safe and complete excision of select benign PPS tumors while minimizing surgical morbidity.