Myiasis is an infestation caused by larvae of dipteran insects, usually flies, that develops within dead or living tissue of vertebrates. It can affect both animals and humans, potentially leading to severe damage. This condition is uncommon in high-income and temperate countries, such as those where our team operates.

Hereby we report a case of myiasis occurred in an elderly patient, suffering from advanced cutaneous neoplasia of the parotid and auricolar region, as well as Chronic Lymphocytic Leukemia.

Of note that the larvae identified on our patient, and located in the left auricle and parotid district, belonged to a fly genus - Musca - with low pathogenetic potential, thus representing a case of facultative myiasis. Treatment consisted of extensive surgical debridement, antiparasitic therapy, and antibiotic coverage, with excellent overall response.