Objective:
To compare the demographic data of patients on PD versus HD
To Carry out a comparative analysis of the important variables that are manifested in disturbances in mineral bone metabolism in CKD patients that are undergoing HD versus PD

Methods: Data was collected quantitatively. The groups were comparable with respect to underlying disease and demographic characteristics. The variables studied were, serum calcium levels, phosphorus levels, vitamin D levels, parathyroid hormone levels, serum albumin, hemoglobin levels and the urine output. It was also established whether the patients were on phosphate binders or not. The decline of residual renal function during dialysis and its relationship with mineral metabolism has been evaluated.

Results: The results of the study showed no difference in gender distribution in the two modalities. Majority of the patients on hemodialysis and peritoneal dialysis are above 35 years. The youngest patient – 11 years is on APD. 90% (n=43) of the total cases are on CAPD. 47% (n=22) are using 2.5% dianeal solutions. Majority of the PD patients 81% n= 39 did the bag exchange procedure themselves. The study revealed that Patients on PD are on dialysis longer with the longest patient being 18 years on PD. Patients on PD had higher hemoglobin levels. Patients on PD had better residue renal function since thy had bigger renal outputs. The highest level of parathyroid hormone levels was found in PD patients the highest being greater than 2000 pg/ml. Most patients accounting for 88% n=42 in HD and 75% n=36 in PD did not have IPTH checked. Majority of the patients in both PD and HD are not on phosphate binders accounting for 54 % n= 26 in HD and 71% n= 34 on PD. Vitamin D levels were highest in hemodialysis. Most patients accounting for 88% n=42 in HD and 79% n=38 did not have vitamin D levels checked. Majority of the patients on peritoneal dialysis had low albumin levels compared to hemodialysis. 8% of HD patients did not have albumin levels checked as compared to only 2% n=1 on PD. Patients on peritoneal dialysis have higher calcium levels. 10 % n=5 and 25% n= 12 of patients on PD and HD consecutively did not have phosphorous monitored. Patients on hemodialysis had higher phosphorous levels. Majority of patients on PD have diabetes -46% n=22 compared to 38% n= 18 on hemodialysis.

Conclusions: In conclusion, Majority of patients undergoing both peritoneal dialysis and hemodialysis have Hyperparathyroidism, hyperphosphatemia which is one of the indicators of mineral bone disease in CKD. The calcium levels were normal in most of the patients.