Postpartum depression (PPD) is a mental health concern. Postpartum depression can develop during pregnancy, or after giving birth to up to one year. Postpartum depression can be a challenge for the mom involved and often it is misdiagnosed. Postpartum depression can be a bigger challenge if the mom is single or has other factors such as lacking a support system. A review of nursing and health related literature was conducted to explore postpartum depression. The three themes that emerged from the literature are: risks, interventions, and screening. Findings from the initial literature review reveal that a lack of knowledge exists in nursing and patient care practice regarding postpartum depression. The purpose of this rapid review was to promote understanding of factors influencing postpartum.