Introduction: The authors studied the epidemiological and clinical aspects of blindness in primary open-angle glaucoma (POAG) at the Departmental University Hospital Center of Ouémé-Plateau (CHUD-OP).

Method: This descriptive and analytical cross-sectional observational study was carried out in the ophthalmology department of CHUD-OP in Porto-Novo over a period of five years. The population included all patients with unilateral or bilateral blindness related to primary open-angle glaucoma (POAG).

Results: Among the 34,565 patients seen in consultation during the study period, 483 patients were followed for POAG, among whom 104 presented blindness. The frequency of POAG was 1.40%, with a prevalence of blindness linked to POAG of 21.53%, including 16.15% for unilateral damage and 5.38% for bilateral damage. The average age of the patients was 62.78 ± 13.17 years, with a majority of patients without a history (58.65%) and a notable proportion of arterial hypertension (16.35%). Visual loss was the main reason for consultation (47.12%), with an unspecified consultation delay in more than half of the patients. Sociodemographic, clinical and therapeutic data did not show a significant association with blindness.

Conclusion: POAG-related blindness remains a major challenge in ophthalmology, highlighting the importance of early detection for its prevention and effective management.