Oral Health and Dental science
Open AccessDevelopment of an Effective Triantibiotic formulation for Enterococcus faecalis in the Treatment of Endodontic Pathology
Authors: Diana Cristina Aristizábal S, Anabel Giraldo G, Diego Mauricio Tobón C, Elizabeth Cadavid, Diego Fernando Rojas.
Abstract
Introduction: The main objective of endodontic treatment is to minimize the number of microorganisms in the root canal system, to prevent or treat apical periodontitis [1]. The Enterococcus faecalis bacteria, most prevalent in persistent endodontic infections, resists antibacterial medications such as calcium hydroxide and multiconjugate pastes [2]. The increase in possible cases of refractory apical periodontitis due to said resistance has led to the search for alternatives, such as the use of broad-spectrum antibiotics alone or in combination as a possible solution to this problem [3].
Objective: To evaluate the effectiveness of a triantibiotic formulation on the inhibition of bacterial growth of E.feacalis by replacing Minocycline with Amoxicillin, to prevent dental pigmentation without losing the disinfection capacity of said paste.
Materials and Methods: Commercial presentations of the antibiotics and microdilution techniques were used to evaluate the antimicrobial activity against the bacterial strain of E. faecalis.
Results: In this study, Amoxicillin obtained the highest percentage of inhibition on E. faecalis
Editor-in-Chief
View full editorial board →