Objective: To explore the application effect of autologous adipose stem cells in the treatment of human type 2 diabetes.

Methods: A total of 104 patients with type 2 diabetes were enrolled. The study period was from February 2018 to October 2020. They were divided into a reference group of 52 cases (conventional treatment) and a study group of 52 cases (autologous adipose stem cell treatment). The therapeutic effects were compared.

Results: After treatment, the fasting insulin and fasting blood glucose of the study group were better than those of the reference group, P<0.05, the difference was statistically significant. The incidence of adverse reactions in the study group was lower than that in the reference group, P<0.05, and the difference was statistically significant.

Conclusion: Autologous adipose-derived stem cells in the treatment of human type 2 diabetes can effectively control blood sugar level, reduce adverse reactions, and improve drug safety, which has significant application value.