The fascial system represents an intricate network within the human body, comprising both superficial, myofascial and visceral layers. Regional fascial dysfunctions can be related to overuse, trauma, sports activities, stress and posture. Fascial dysfunction has been associated with both diminished range of motion as well as regional pain. Unfortunately, these fascial lesions are not visible on ultrasound or MRI (yet). Glucopuncture, a novel injection technique, involves the administration of 5% sugar water injections to address both range of motion as well as pain. This article presents a 59-year-old female patient with back pain who underwent glucopuncture for dysfunction of the superficial fascia. She experienced significant pain relief (from 6/10 to 0/10) following glucopuncture into pain points found in the dorsal midline. This clinical case highlights the potential of palpation-guided glucopuncture as a simple, cost-effective method for modulating regional pain. However, further research is necessary to fully ascertain the efficacy and safety of glucopuncture for treating fascial pain. We also require more scientific data to explain how exactly these injections
work.