Gynecology & Reproductive Health

Open Access ISSN: 2639-9342

Abstract


Application of DOHaD hypothesis to the Effect of Stress Levels in Pregnant Women on the Fetus and Baby’s Mental Health: A Literature Review

Authors: Kafumi Sugsihita.

Introduction: According to the research of Cadzow et al., on antepartum and postpartum mental health, weak attachment bonding between the fetus and mother during pregnancy was associated with postpartum depression and anxiety. Sugishita et al. found that postpartum depression decreased when attachment to the fetus was higher during the antepartum period. Attachment to the fetus during pregnancy was associated with maternal mental health and was associated not only during pregnancy but with postpartum depression and blood cortisol levels, which are stress indicators, cross over the placenta and have been correlated with maternal and fetal levels. It has been afraied that strong psychological stress during pregnancy has some effect on the fetus and causes mental development in children, and the fetal programming hypothesis is pointed out in the background. However, there has been no previous research on the relationship between mental health such as stress in pregnant women and the fetal programming hypothesis. The purpose of this study is to examine the relationship between stress in pregnant women and the fetal programming hypothesis through literature.

Methods: The databases used in the literature search are Pubmed, CINAHL, Cochrane Library, and Google Scholar. The search range is from 2000 to 2020. The criteria for adopting the document are 'DoHaD' x 'Mental Health', 'DoHaD' x 'Stress', and 'DoHaD' x 'Depression' in the English original article registered in the retrieved database. Among the retrieved articles, duplicate documents were excluded as a result of animal experiments and genome analysis. As a result, 13 articles were selected.

Results & Conclusion: As a result of conducting a literature review, it was found that when the stress of the pregnant woman is physically and psychologically high, the stress of the child is high. In particular, fetal dysfunction is likely to occur during labor if you spend pregnancy period when pregnancy complications and anxiety are strong. It is still necessary to examine the relationship between the child's growth and mental illness and the stress she received as a mother at the time of the fetus.

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