Journal of Medical - Clinical Research & Reviews

Open Access ISSN: 2639-944X

Abstract


High Protein Kinase B (Akt) Concentration in Attention Deficit Disorder

Authors: Russo AJ, Albert Mensah, Judith Bowman, James Lukasik.

Attention-deficit hyperactivity disorder (ADHD) is characterized by inattentiveness, hyperactivity, and impulsivity. It has been suggested that the mTOR pathway, which downstream includes activation of Akt, is involved in ADHD. In this study, we measured the concentration of phosphorylated Akt in 55 ADD patients and 32 neurotypical controls using an ELISA. We found that Akt levels were significantly higher in the ADD group and may be important to the etiology of ADD/ADHD.

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