Metabolic syndrome (MetS) represents a cluster of interconnected risk factors for cardiovascular disease and type 2 diabetes mellitus. This review1 examines the emerging evidence on the role of micronutrients in the pathophysiology, prevention, and management of MetS. Recent research has highlighted significant associations between micronutrient status and the components of MetS, including insulin resistance, dyslipidemia, hypertension, and central obesity. This review synthesizes findings from studies published between 2015 and 2025, focusing on vitamins (D, B complex, E, C), minerals (magnesium, chromium, zinc, selenium), and other bioactive compounds. Current evidence suggests that micronutrient deficiencies may contribute to the development and progression of MetS, while targeted supplementation strategies show promise as adjunctive therapeutic approaches. We discuss potential mechanisms of action, clinical implications, and future research directions to elucidate the complex interplay between micronutrient status and metabolic health.